SOLUTION

img03The CRYSTAL-VIS project aims to develop an imaging-based physical characterisation device capable of providing all the physical characteristics of a crystal in-line in a crystallisation process. The application of both novel optical approaches and pattern recognition methods will enable accurate monitoring of crystallisation parameters such as size and shape distributions. The R&D effort will centre on engineering design, software/algorithm design, user interface design; and integration and validation in API manufacturing facilities.

To this end, over the course of the two years of this project a device that can identify and characterise the physical properties of particles / crystals within a liquid environment will be designed, realised and tested.

The proposed method combines fast on-line image capturing technique and contrast enhancement microscopy methods for creating an information rich image. Applying novel pattern recognition methods enables detecting and characterizing crystals in-line with high accuracy.