The CRYSTAL-VIS project will develop a novel Process Analytic Technology device capable of providing all the physical characteristics of a crystal in-line in a crystallisation process.
The 2 year research project is funded by the European Commission and brings together 8 partners from 3 European countries. The aim is to bring a real time monitoring system for the physical characteristics of API crystals.
An active pharmaceutical ingredient (API) is the substance in a pharmaceutical drug that confers pharmacological activity. The manufacture of pharmaceutical products based on small-molecule API remains critical to global healthcare.
API manufacturing is a complex process and may consist of many steps such as, hydrogenation, crystallisation, filtration, drying, milling etc., all of which need to be tightly controlled in order to assure product quality.
The CRYSTAL-VIS will develop a revolutionary imaging-based physical characterisation device that will provide the API industry with real-time information of all crystal physical characteristics in-line in a crystallisation process, thereby allowing this critical of processes for the behaviour of the end-product to be controlled.
The CRYSTAL-VIS project aims to develop an imaging-based physical characterisation device capable of providing all the physical characteristics of a crystal in-line in a crystallisation process.read more